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Product Description
Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.
Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.
Product Name: |
Butylcarbazate BOC-hydrazide t-Butyloxycarbonyl-hydrazide Boc-hydrazine tert-Butoxycarbonylhydrazine tert-Butyl hydrazinocarboxylate tert.-Butylcarbazate Hydrazinoformic acid tert-butyl ester Hydrazine carboxylic acid T-butyl Tert-Butyloxycarbonyl-hydrazide Tert-Butoxycarbonyl Hydrazide tert-butyl hydrazinecarboxylate 1-tert-butylhydrazinecarboxylate |
CAS: |
870-46-2 |
EINECS: |
212-795-3 |
MF:(molecular formula) |
C5H12N2O2 |
MW:(molecular weight) |
131.154 |
MOL File: |
870-46-2.mol |
InChIkey |
DKACXUFSLUYRFU-UHFFFAOYSA-N |
tert-Butyl carbazate CAS 870-46-2 Chemical Properties |
|
Melting point |
39-42 °C (lit.) |
Boiling point |
63-65 °C/0.1 mmHg (lit.) |
Density |
1.02g/mLat25°C(lit.) |
Flashing point |
92.994°C /197 °F |
Water solubility |
Soluble in ethanol and methanol. |
Vapor pressure |
0.024mmHg at 25°C |
Refractive index |
n20/D1.4496(lit.)(estimate) |
Storage temp. |
-20°C |
Form |
Crystalline Lumps |
Color |
White to slightly yellow |
Sensitive |
Moisture Sensitive |
BRN |
1756967 |
InChIKey |
DYHSDKLCOJIUFX-UHFFFAOYSA-N |
CAS DataBase Reference |
870-46-2(CAS DataBase Reference) |
EPA Substance Registry System |
Hydrazinecarboxylic acid, 1,1-dimethylethyl ester (870-46-2) |
● High purity >99%
● Stable supply capability: 1000tons/Year
● Standard packaging and storage
● Warranty: if there are quality problems, we can negotiate a refund or exchange
Colorless crystal, flammable, stored at 0~4℃.Phenyl chloroformate (C6H5OCOCl) is added dropwise to the mixed solution of tert-butanol, quinoline and dichloromethane (as solvent) to produce tert-butyl phenoxyformate [(CH3)3COCOOC6H5] first, which is then reacted with hydrazine to produce. It is used as a key intermediate in the production of tert-butyl azidocarboxylate.
Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 is a very important intermediate used in the synthesis of many tricyclic and above tricyclic compounds, and is widely used in the pharmaceutical, polymer compound and dye industries. In addition, Tert-Butyl carbazate is an important raw material for the synthesis of acyl hydrazinyl derivatives.
● Employed in a palladium-catalyzed cross-coupling with vinyl halides leading to N-Boc-N-alkenylhydrazines.
● Reagent used in solid phase peptide synthesis and in α-amino aldehyde optical purity determinations. Condenses with aldehydes to form hydrazones which are intermediates in the synthesis of HIV-1 protease inhibitors.
● Synthesis of amino acid protectants
● Raw material for the preparation of BOC-azide, a reagent for introducing BOC amino acid protection.
● Also used as a reagent for synthesizing sulfonyl hydrazides and carboxy hydrazides.
● Used in palladium-catalyzed cross-coupling reactions with vinyl halides
● to produce N-tert-butoxycarbonyl-N-alkenyl hydrazine.
● Reagent for solid-phase peptide synthesis and optical purity determination of alpha-amino aldehydes.
● Can be condensed with aldehydes to form hydrazones, which can be used as intermediates in the synthesis of HIV-1 protease inhibitors
● Dangerous Goods Marking T-F,T,F
● Hazard Class Code48-36/37/38-24/25-11
● Safety Description45-36/37/39-16-24/25Chemicalbook
● Dangerous Goods Transport Number 1325
● WGK Germany 3
● F21
● TSCA Yes
● HazardClass 4.1
● PackingGroupIII
● S16 - Keep away from sources of ignition.
● S36/37/39 - Wear appropriate protective clothing, gloves and goggles or mask.
● S45 - In case of accident or discomfort, seek immediate medical attention (if possible, show its label).
● R11 - Highly flammable.
● R36/37/38 - Irritates eyes, respiratory system and skin.
● R48 - Serious health hazard from prolonged exposure.
Export Market(Overseas Market)
● Main markets
● North America includes the United States, Canada, and Mexico
● Europe includes Belgium, Germany, France, UK, Italy, Spain
● South America includes Colombia, Argentina, Brazil, and Chile
● The Asia Pacific includes Japan, China, Korea, India, Saudi Arabia, and Southeast Asia
● What exhibitions have we participated
● API 2017 2018 2019 2022 online, China,Germany, Japan
-Our Policy "We care quality, we care life"
-Delivery: By air or sea (DHL, UPS, FeDex, TNT...)
-Warranty information: if there are quality problems, we can negotiate a refund or exchange
Payment method
● TT/ LC/Paypal,Western Union...
Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Packing
In 25kgs or 30kgs net plastic drum, or steel drum, according to customer’s requests.
Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Transport
Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Storage
● Store in freezer, under -20°C.
● Keep in dark place, Inert atmosphere
Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Precautious:
P240 : Ground/bond container and receiving equipment.
P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking.
P241 : Use explosion-proof electrical/ ventilating/ lighting/ equipment.
P280 : Wear protective gloves/ eye protection/ face protection.
P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 is an organic compound that belongs to the class of trifluoroacetic acids. It has been shown to inhibit the Mcl-1 protein, which is a key regulator of mitochondrial membrane potential and is involved in cell death. Tert-Butyl carbazate also inhibits the growth of K562 cells by binding to their nucleic acids. The reaction solution containing tert-butyl carbazate was found to be more effective at inhibiting inulin uptake than a solution containing a different trifluoroacetic acid. This could be because it inhibits the biological function of inulin, which is the transport of glucose across cell membranes.
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